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Research

The Department of Pathology is deeply invested in scientific efforts to improve treatments in our field. Learn more about our department’s investigations below.

Message from the Vice Chair

"We are driven by a shared passion for discovery and a deep commitment to advancing human health through innovative research programs and collaborative partnerships among scientists and pathologists."

Peng Ji, MD, PhD
Vice Chair of Research 

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Areas of Research

Members of the Department of Pathology are defining the cellular and molecular basis of disease toward the development of new and improved strategies to diagnose and treat, inherited, acquired and infectious disorders. Learn more about the work being done in our labs via the descriptions below.

Affilated Research Centers and Institutes

The faculty members of Northwestern University Feinberg School of Medicine’s Department of Pathology are engaged in research within the department and throughout Northwestern Medicine and Northwestern University. Our work throughout the community, including director appointments, illustrate the importance we put on scientific collaboration.

Research Cores

Core facilities provide cost-efficient access of state-of-the-art equipment, the most current technologies and expert technical advice to individual scientists.

Learn more about our affiliated cores

Recent Publications

5TH EDITION OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES.

Miranda RN, Amador C, Chan JKC, Guitart J, Rech KL, Medeiros LJ, Naresh KN; WHO 5(th) edition classification project.

Mod Pathol. 2024 May 9:100512. doi: 10.1016/j.modpat.2024.100512. Online ahead of print.

Follow-Up Biopsies in Gastrointestinal Immune Checkpoint Inhibitor Toxicity May Show Markedly Different Inflammatory Patterns Than Initial Injury.

Tomm NK, Szczepanski JM, Fang JM, Choi WT, Xue Y, Setia N, Karamchandani DM, Cheng JY, Westerhoff M.

Hum Pathol. 2024 May 9:S0046-8177(24)00085-6. doi: 10.1016/j.humpath.2024.05.001. Online ahead of print.

Fractionated radiation therapy alters energy metabolism and induces cellular quiescence exit in patient-derived orthotopic xenograft models of high-grade glioma.

Huang ZL, Liu ZG, Lin Q, Tao YL, Li X, Baxter P, Su JM, Adesina AM, Man C, Chintagumpala M, Teo WY, Du YC, Xia YF, Li XN.

Transl Oncol. 2024 May 10;45:101988. doi: 10.1016/j.tranon.2024.101988. Online ahead of print.

Ultrasensitive and Rapid Circulating Tumor DNA Liquid Biopsy Using Surface-Confined Gene Amplification on Dispersible Magnetic Nano-Electrodes.

Park BC, Soh JO, Choi HJ, Park HS, Lee SM, Fu HE, Kim MS, Ko MJ, Koo TM, Lee JY, Kim YK, Lee JH.

ACS Nano. 2024 May 11. doi: 10.1021/acsnano.3c12266. Online ahead of print.

The Evolving Classification of Meningiomas: Integration of Molecular Discoveries to Inform Patient Care.

Trybula SJ, Youngblood MW, Karras CL, Murthy NK, Heimberger AB, Lukas RV, Sachdev S, Kalapurakal JA, Chandler JP, Brat DJ, Horbinski CM, Magill ST.

Cancers (Basel). 2024 Apr 30;16(9):1753. doi: 10.3390/cancers16091753.

Genetic Underpinnings of Cuticular Hydrocarbon Biosynthesis in the German Cockroach, Blattella germanica (L.): Progress and Perspectives.

Pei XJ, Schal C, Fan YL.

J Chem Ecol. 2024 May 10. doi: 10.1007/s10886-024-01509-7. Online ahead of print.

Histologic Features of Mycobacterial Spindle Cell Pseudotumors: A Multi-institutional Clinicopathologic Analysis of 14 Cases.

Szczepanski JM, Lieberman JA, Lamps LW, Gonzalez RS, Xue Y, Zhang X, Yilmaz OH, Hart J, Krausz T, Mantilla JG, McHugh JB, Westerhoff M.

Am J Surg Pathol. 2024 May 10. doi: 10.1097/PAS.0000000000002234. Online ahead of print.

Adrenal pheochromocytoma impacts three main pathways: cysteine-methionine, pyrimidine, and tyrosine metabolism.

Lai C, Yang Q, Zhang Y, Gong R, Wang M, Li J, Lai M, Sun Q.

J Zhejiang Univ Sci B. 2024 Mar 12;25(5):410-421. doi: 10.1631/jzus.B2300579.

Exploring the properties and potential of the neural extracellular matrix for next-generation regenerative therapies.

Ortega JA, Soares de Aguiar GP, Chandravanshi P, Levy N, Engel E, Álvarez Z.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2024 May-Jun;16(3):e1962. doi: 10.1002/wnan.1962.

Mitochondria regulate proliferation in adult cardiac myocytes.

Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Beussink-Nelson L, Shah SJ, Ofman G, Wasserstrom JA, Muller WA, Misharin AV, Budinger GRS, Abdala-Valencia H, Chandel NS, Dokic D, Bartom ET, Zhang S, Tatekoshi Y, Mahmoodzadeh A, Ardehali H, Thorp EB, Schumacker PT.

J Clin Invest. 2024 May 9:e165482. doi: 10.1172/JCI165482. Online ahead of print.

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